Bird Flu: Why Modern Medicine Won't Save Us

Very often when people begin to learn about bird flu,they did reduce deaths from pneumonia a bit, by up
they jump to the conclusion that because medicineto 30 percent.”
has advanced by quantum leaps since the 1918-19According to the Influenza Vaccine Supply (IVS)
influenza pandemic (global epidemic), there is nothingInternational Task Force, “Whatever scenario,
to worry about. They are certainly right about theeven the most optimistic, the worldwide [vaccine]
advance of medicine, which has been extraordinaryproduction capacity will be clearly insufficient in case
by any measure. Unfortunately, when it comes toof pandemic.”
dealing with a bird-flu pandemic, these advances fall7. Shortages of nurses and other healthcare
short in many areas. To name the most significant:personnel will be significant, because of overexposure
1. Bird flu is caused by an influenza virus, for whichto people with bird flu—and thus a higher illness
there are only four approved antiviral agents in theand death rate among healthcare workers, and
U.S. The virus has extensive resistance to two ofbecause a high proportion will simply decide not to
these medicines already, and resistance mightcome to work. A similar situation occurred in New
develop in the remaining two once they are usedOrleans during Hurricane Katrina when 250 members
more widely in a pandemic. The two remainingof the police department (one-sixth of the force)
medicines, Tamiflu (oseltamivir) and Relenzaabandoned their jobs during the hurricane and
(zanamivir), are in extremely short supply and, evenflooding. It also happened in Toronto during the SARS
with planned increases in their manufacture, willoutbreak, when some nurses and other healthcare
remain in short supply for many years to come.workers submitted their resignations (although many
These medicines must be given within 48 hours ofwere persuaded to stay).
the onset of symptoms, which can be difficult toThe shortage of nurses, which is already a big
accomplish for a variety of reasons. Even when theyproblem in the United States, was highlighted recently
are available and given on time, their effectiveness isby Keji Fukuda of the influenza branch of the
less than 100 percent. And because bird flu is veryCenters for Disease Control and Prevention (CDC).
different than the usual influenza we are used to,According to Fukuda, scientists are racing to prevent
higher doses given for longer periods of time may bewhat could be millions of deaths from a flu pandemic,
necessary for optimal effect.but what could trip them up is the simple lack of
2. While we have many wonderful antibioticnurses and hospital beds. He said, “No matter
medicines, these are not effective against bird flu,how good medical technology is, if we don’t
because antibiotics treat only bacterial infections, nothave healthcare workers to care for sick people and
viral infections. Antibiotics can be used to treathospital beds to put them in, it’s not a good
bacterial infections that develop after viral infectionssituation.”
have damaged the body, allowing bacterial infectionsAnd it’s not only the limited numbers of
to “take over.” This can happen, fornurses—it’s also a question of whether or
example, when viral pneumonia turns into bacterialnot healthcare workers would come to work during a
pneumonia. However, this did not happen in thebird-flu pandemic. A recent article (b) reported the
1918-19 Spanish flu to any extent, nor in the 2003disturbing findings of a survey of 6,000 healthcare
SARS pandemic, and it doesn’t appear to be aworks in and around New York City:
significant factor in the deaths that have occurred so“One assumption blown away by Hurricane
far from bird flu. Hence all our sophisticated antibioticsKatrina is that if government does nothing else, at
will not be of much help with bird flu.least it protects people’s health and safety.
3. The most common cause of death from theThe Mailman School of Public Health at Columbia
1918-19 influenza pandemic, the SARS pandemic, andUniversity in New York City set out to look at how
from bird flu is acute respiratory distress syndromemany healthcare workers said they would show up
(ARDS). The viruses from these diseases causefor work, depending on the type of emergency.
severe damage to lungs, which results in ARDS.There was some good news: 87 percent of 6,000
Numerous treatments have been tried but generallyworkers surveyed in 47 facilities in and around New
have failed. Patients with ARDS require mechanicalYork said they would be able to go to work in the
ventilatory support, meaning they need to be on aevent of a mass casualty incident, and 81 percent for
mechanical respirator. These are expensive machines,an environmental disaster.
and the supply in the United States is only slightlyOnly 61 percent, however, would show up for a
above demand during the normal flu season. Simplysmallpox epidemic, just 48 percent during a SARS
put, when the bird-flu pandemic strikes, thereepidemic and 57 percent during a ‘radiological
won’t be enough of these machines, and soevent.’
people who develop ARDS will not have access toThat’s a problem, isn’t it? Less than half
this potentially life-saving treatment.of healthcare workers expect to work during a
4. There won’t be enough isolation rooms toSARS [or bird-flu] epidemic, and less than two-thirds
place the large numbers of patients with bird flu in,if terrorists set off a so-called dirty bomb in the
which will result in more people becoming ill throughfinancial district.
exposure to people with bird flu. Likewise, there‘Although we might assume that healthcare
won’t be enough of some medical equipment,employees have an obligation to respond to these
because of increased demand for some itemshigh-impact events, our findings indicate that personal
coupled with decreased supply—because of ourobligations, as well as concerns for their own safety,
reliance on a global supply chain, foreign manufacture,play a pivotal role in workers’ willingness to
and just-in-time delivery. There won’t bereport to work,’ said Kristine Qureshi, a
enough personal protective equipment (such asresearcher in the epidemiology department at
disposable gloves, N95 face masks, gowns, faceColumbia.”
shields or goggles, head caps, and shoe covers),And so “modern medicine,” no matter
which will increase exposure and infection.how advanced, will clearly have difficulty dealing with
5. During the coming pandemic, there won’t bea bird-flu pandemic. In a sense, the next pandemic
enough beds in hospitals for all the sick people withcould very well be analogous to the Hurricane Katrina
bird flu. Makeshift “hospitals” will have tosituation, with mass confusion, lack of resources,
be established outside of existing hospitals to carevisible dead bodies, acts of cowardice and acts of
for all the ill patients.heroism, financial disaster, panic, and every emotion
6. An effective vaccine has yet to be developed, andpossible—nothing like we are used to witnessing
the chances that one will be developed before ain America; shocking.
pandemic emerges are practically nonexistent. Once aPartly because of the limitations of both government
vaccine is developed, it will be months into theand healthcare capabilities, individuals need to prepare
pandemic, and many people will already have becomefor the coming bird-flu pandemic themselves. There
ill. Because we have no natural immunity to this neware four specific areas that must be addressed, as I
virus, we might need two immunization shots tohave written in an earlier article (which can be
develop sufficient immunity. This makes implementingaccessed on our Web site.)
an immunization program more difficult, and(a) Rosenthal E: 2 Studies Find Flu Treatments Fall Far
decreases the amount of vaccine available forShort. International Herald Tribune. September 22,
everyone.2005. Available at: Accessed on September 23, 2005
Vaccines, like antiviral medicines, are not 100 percent(b) Olmsted D: Health wrap: of disasters and diseases.
effective in either preventing infection or minimizingMonsters and Critics News, September 9, 2005.
symptoms once infected. A startling new report (a)Available at: Accessed on September 15, 2005
found only limited benefit from influenza vaccines:Bradford Frank, M.D., M.P.H., M.B.A.
“In people over 65, the vaccines ‘areThe Frank Group
apparently ineffective’ in the prevention ofP.O.
influenza, pneumonia and hospital admissions, although