| Unbalanced Translocation | | | | can just be lost or it can get attached to a different |
| When a part of a chromosome breaks and attaches | | | | chromosome. |
| to a different chromosome, the process is referred | | | | Inversion |
| to as translocation. If there is no loss or gain of | | | | A chromosome can break at more than a single point |
| material during this process, it is called balanced | | | | sometimes. When it does at two points in the arm, |
| translocation which does not affect the individual. | | | | this broken portion can flip, invert and reattach to |
| However, when there is a loss or gain, it refers to | | | | the chromosome. Owing to the reversal in genetic |
| unbalanced translocation and results in a genetic | | | | code in this particular section, there are chances for |
| disorder. In case of the occurrence of a balanced | | | | the occurrence of the syndrome. |
| translocation in a parent, there are 10% chances for | | | | Duplication/ Partial Trisomy |
| unbalanced translocation to occur in the new-born | | | | A portion of the short arm in the chromosome |
| child. But there are also cases, wherein the child | | | | number five can get duplicated at times and when |
| experiences a de novo or spontaneous unbalanced | | | | this includes the critical region of the chromosome, it |
| translocation at times. | | | | can result in a disorder. The duplicated portion will |
| | | | attach within the chromosome or at its ends and the |
| In some rare cases, there are chances where the | | | | code will be misread. |
| chromosome just loses a part or piece from each of | | | | Mosaicism |
| its ends and these ends can unite to form a ring. In | | | | In rare cases, the deleted chromosome can be |
| the child who possesses cri du chat syndrome, this | | | | present in some cells of our body rather than in all. |
| ring can lead to further problems based on the | | | | This content may vary like 20% or 75%. Based on |
| amount and length of genetic material lost. And | | | | the occurrence of the deletion in the types of body |
| especially, when the loss is from the chromosome's | | | | cells and the percentage of occurrence, the child can |
| long arm, it is very likely to result in the occurrence | | | | either be mildly or severely affected. This case |
| of the syndrome. | | | | presents a difficult diagnosis, since the portion of |
| Interstitial Deletion | | | | blood or tissue sample collected must contain the |
| In some other cases, a portion from inside of the | | | | cells with deletion or it would result in a wrong |
| short arm of the chromosome can get deleted or cut | | | | diagnosis. |
| and the broken ends can rejoin. The cut off portion | | | | |