How Modern Microscopes Are Used in the Laboratory

The lab microscope is essential to every scientist,magnified image which allows for a more detailed
and is used everywhere today from medical labs toimage of the specimen. By using a particle beam the
schools. Microscopes have been in use since the midelectron microscope illuminates the object for easier
seventeenth century, and were used by Anton Vanviewing. Many of these microscopes have superior
Leeuwenhoek in his observations of some of themagnification due to the simple fact that electrons
first microorganisms. Those early microscopes hadhave shorter wave lengths than light, allowing for a
only a single lens and were extremely simple, allowingmagnification of almost 1,000,000x rather than the
only the briefest glimpse into the fascinating world of1000x magnification of light.
the microcosm.Electron microscopes come in several varieties, such
Today lab microscopes can range from a simpleas the transmission electron microscope, which, with
compound microscope with two lenses, to morea high voltage electron beam emitted by an electron
complex, digital microscopes that come with cameras,gun, can get a magnification of over 50 million times.
motion recorders and laser scanners. Many labs haveIt is primarily is used in nano-technologies. However,
multiple microscopes, each used for a set purpose, aselectron microscopes are expensive to operate,
some work better than others in certain situations.requiring high voltages and a water supply for cooling
There are two primary categories of labthe lenses and pumps. Since vibrations and magnetic
microscopes, light microscopes and electronfields can interfere with their readings, these
microscopes, though there are many variations inmicroscopes must be carefully housed in stable
each. A light microscope uses rays of light, magnifiedbuildings or underground.
and focused through a series of lenses. A commonLab microscopes can even be hooked up to
example is the compound light microscope, used tocomputers which can be useful in enhancing an image.
examine thinly sliced sections. With this labSome come with cameras, 3D functions and LCD
microscope the specimen is lit from beneath, withmonitors to allow you to see your specimen with
light passing through clear sections but not thegreater ease. With integrated software you can do
opaque ones. Many times the sample may be dyedmore than simply make observations, you can track
to allow certain cellular structures to better absorbdata, measure the dimensions and shapes of your
light.specimen, and even print favorite images.
One popular light microscope is the biologicalLab microscopes have come a long way since then,
microscope, used in medical labs as well as clinicalgrowing in complexity as our understanding of the
laboratories and schools. These are simpleworld increases. We are now able to study not just
microscopes used most often in the studies ofcells, but proteins, electrons, particles and viruses. We
viruses, pathogens and other changes in cell tissuesare even able to, with the atomic force microscope,
as well as bacteria. However, for more complexnow see microorganisms with true, three dimensional
observations at a smaller level, a different type of labsurface profiles without having to treat the specimen
microscope can be used.with either metal or carbon coatings that would
An electron microscope uses an electronicallydamage or change the sample and its readings.