In vitro propagation and antibacterial activity test of Ipomoea turpehum

Introduction:chloride (HgCl2) Solution plus 3-4 drops of Tween 20
Operculina turpethum (syn. Ipomoea turpethum,in 100 ml for 8 min with gentle shaking. Sterilized
convulvulaceae) is large evergreen perennial climberexplants will be washed 4-6 time with sterile distilled
blooms with fragrant showy flowers. The plant iswater to remove the effect of mercuric chloride.
native to Indian subcontinent although it can also beThen the explants will be cultured in MS medium (
found in the Pacific Islands, China and Australia . InMurashige and Skoog, 1962) containing different
Bangladesh, found in the north-westtern districts andconcentration and combinations of BAP, Kin, NAA,
Chittagong homestead shrubberies. A resinousand GA3 for multiple shoot induction . The induced
substance (turpethin) obtained form root bark of theshoot will be sub cultured in medium having different
plant is a mild purgative and used in cases of debility,combination of GA3 and Kin for proper elongation.
toxicity, etc (Ahmed, 1997). Paste of the root is usedRoots will be induced and proliferated in developed
as an external application in hemorrhoids, chancresplantlets using different concentrations of IAA and
and ulcerations. Oil extracted from the root bark isIBA.
used in diseases of a scaly nature. The fresh juice of 
leaves is dropped into the eyes for inducing  Economic importance of the proposed research:
lachrymation in opthalmia. Unfortunately, this veryIn our commodities the Economic importance of
important medicinal plant now enlisted as endangeredIpomoea turpethum is increasingly in great demand.
species in Bangladesh and its neighboring countriesBecause it has medicinal importance. The active
(Ahmed, 1997). In vitro culture method provides newprinciple of the leaves is a cardiotonic substance
means of conserving and rapidly propagating valuable,named oleandrin. It has anti-inflammatory and
rare and endangered medicinal plants (Nalawade et al.,stimulant properties. The roots, bark and seeds
2003). A well-established protocol including plantcontain cardio-active glycosides, formerly designated
regeneration from tissue, organ etc. Would help plantas neriodorin, neriodorein and karabin, which are
population from being extinct. The advantage of theanti-inflammatory and stimulant, good pain relievers. A
technique are the space exploitation, thepaste of the root is used as an external application in
improvement of the sanitary conditions of the plantshemorrhoids, chancres and ulcerations. Oil extracted
and the facilitation of international germplasmfrom the root bark is used in skin diseases of a scaly
exchange ( Alderete et al., 2006).nature. The fresh juice of leaves is dropped into the
A revision of the available literature showed noeyes for inducing lachrymation in ophthalmia. This
previous report on tissue culture of this importantdemand is increasingly becoming acute because of
species. Consequently, the developed tissue culturetheir non-availability, owing to adverse climatic
technique will increase the scarce knowledge aboutconditions, pests, and political instability in cropping
the in vitro responses of this native germplalm withareas, misuse and overexploitation. Man medicinally
potential relevance as an endangered medicinal plant.important plants are already threatened in their
 natural habitats. There is a growing need to preserve
Materials methods:these plants either in vivo or in vitro because of the
 Shoot tip and nodal segments of field grown plantsuniqueness of this species.
will be used as experimental materials.  MS medium1. References:
with different combination and concentration of1. Ahmed, N.1997. Wild flowers of Bangladesh. The
growth regulators will be used for massive microUniversity press linited , University of Dhaka.
propagation, Callus will be also induced using in vitro2. Alderete et. al. 2006. Establishment of an in vitro
explants. Culturing nodal segments having auxiliary bud micropropagation protocol for  Mecardonia tenella .
of mature pants has carried out micro propagation of Elect. J. Biotechnol. 9(3):263-266 (special isssue).
Ipomoea turpethum. Plant materials will be collected3. kapil, A , Koul, I.b. Banejee, S.K. and Gupta, b.d.,
from wild population of Rajshahi University Campus,Antihepatotoxic effects of major diterpenoids
Bangladesh Initially; the collected nodes will beconstituents of Andrographis paniculata.  biochem.
washed with Savlon (commercial disinfectant, ACIPharmacol.,1993,46,182-185.
Parma, Bangladesh) for 5 min followed by treatment4. Murashige, T. and F. Skoog. 1962. A revised
with 70% v/v in ethanol for 3 min in shaking. Finallymedium for rapid growth and bioassay with tobacco
the explants will be sterilized 0.1% w/v mercurictissue culture. Plant Physiol. 15: 473-497.