| Chronic rapidly increasing obesity has become a major | | | | problems, increased risk of certain cancers. Other |
| public health problem in industrialized countries. The | | | | disorders such as cholesterol, sleep apnea, |
| World Health Organization (WHO) has called obesity | | | | osteoarthritis, infertility, venous insufficiency, reflux |
| epidemic first non-infectious history. Its management | | | | esophagitis is frequently associated with obesity. In |
| is seen as a priority, and even more so than being | | | | the United States for example, overweight is |
| overweight affects individuals of younger and | | | | responsible for the increase in diabetes among people |
| younger. | | | | in their thirties, in the space of ten years, this disease |
| Data collected by WHO showed that nearly half of | | | | has increased 76% in this age group and 33% in the |
| Americans are overweight, while a quarter of the | | | | general population. Among children, too, a form of |
| population is frankly obese, a figure that may reach | | | | ultra-early diabetes type 2 appeared a few years |
| 70% of some populations. Europe is not spared, with | | | | ago, which is growing alarmingly. The first cases of |
| 30% of adults overweight, obesity affecting 12% of | | | | atypical diabetes have been detected in France in |
| adults in Western Europe. In France, the prevalence | | | | 1999 and the new disease is spreading. |
| of obesity has increased by about 45% between | | | | The treatment of obesity does not limit itself to |
| l987 and 1996, and the number of obese individuals is | | | | solve a weight problem, but is to take charge of the |
| estimated at 8 million. Obesity also affects the young | | | | medical problem in its entirety. These treatment and |
| population, since the number of obese children has | | | | prevention of physical disorders while developing a |
| doubled since the 80s, and the prevalence of obesity | | | | program tailored to weight loss. Recall that the |
| is estimated at 10-12% in children aged 6 to 12 years. | | | | approach of drug treatment of obesity is |
| Some studies predict that at this rate half the | | | | controversial. Medications such as diuretics, |
| European population is affected by obesity by 2030. | | | | anorexigenic catabolic and promote weight loss but |
| Obesity is a condition characterized by excess body | | | | do not act specifically on the reduction of fatty |
| fat (or fat). An international standard has been | | | | tissue. In addition, generally effective in early |
| adopted for measuring overweight and obesity. This | | | | treatment, they have not proven long term. And in |
| is the Body Mass Index (BMI), defined as weight | | | | many cases, they are the cause of severe metabolic |
| divided by the square of height in kg/m2 (see box). | | | | disturbances, and therefore strongly discouraged. |
| BMI estimates the degree of obesity and thus allows | | | | Thus, diuretics that force the kidneys to excrete |
| to assess the health risk (co-morbidity) associated | | | | more water can cause serious electrolyte imbalance, |
| with it (see box). A person is considered obese when | | | | or dehydration. The catabolic can be toxic, causing |
| this value is greater than or equal to 30 kg/m2. In | | | | side effects on the heart and central nervous |
| addition to BMI, it should also measure the distribution | | | | system. The anorectic can lead to addiction and |
| of body fat. Indeed, it is now accepted that the | | | | other psychological disorders they were removed |
| presence of excess fat in the abdomen causes an | | | | from the European market at the beginning of the |
| increased risk to health. Thus, a waist circumference | | | | year. |
| exceeding 88 cm in women, and 102 cm in men, | | | | A new treatment acting on the gastrointestinal tract |
| indicating visceral obesity and increased risk of | | | | to block fat absorption in part by the agency was |
| developing other clinical problems. | | | | recently prescribed. Other molecules are under |
| The reasons for the development of obesity are | | | | development or after marketing procedure. Finally, in |
| many. Obesity is a multifactorial symptom resulting | | | | some cases, the severity of obesity is such that |
| from complex interactions between a genetic and | | | | surgery on the stomach is stimulated, the |
| more or less conducive environment in which it | | | | gastroplasty. It aims to reduce food intake by |
| operates. Indeed, the heritability of fatness is | | | | reducing gastric volume: the stomach and divided into |
| undeniable. Certain subjects resist obesity whilst | | | | two compartments, like an hourglass, the narrow |
| others are particularly sensitive to changes in diet and | | | | passage is created using a ring. Considering its effect |
| its fat content. For example, an overweight child with | | | | on weight loss and reduction of associated |
| at least one obese parent has a 80% risk of | | | | pathologies, it seems that the effectiveness of |
| becoming obese as adults, against only 10% chance if | | | | gastroplasty in the short and medium terms is |
| both parents were poor. | | | | recognized. But among experts, Some wonder about |
| The various family analysis concluded that there was | | | | the soundness of a surgical measure in response to a |
| a small number of genes playing a role in body size | | | | behavioral problem. |
| and regional distribution of body fat. The results of | | | | However, medication does not solve the problems of |
| research of the past three years suggest the | | | | weight and not "cure" not obese. They must be |
| involvement of a score of different genes or | | | | medically monitored, and enroll in a comprehensive, |
| chromosomal regions. This means that the | | | | involving diet and regular physical activity. It is now |
| biochemical and physiological systems responsible for | | | | commonly accepted that the diet must be |
| the formation of obesity are multiple and occur at | | | | customized, that is to say into consideration the |
| different stages of energy regulation. The human | | | | habits and feeding behavior of each individual, but |
| genome and advances in molecular genetics should | | | | also realistic, since it is imperative that they are |
| therefore allow to classify the "obesity" based on the | | | | long-term. |
| metabolic mechanisms put into play. | | | | In industrialized countries, the economic cost of |
| However, research suggests that genetic factors are | | | | obesity and associated diseases is 2.4 to 5% of |
| involved themselves in less than one third of cases | | | | health spending. Of course, the numbers vary |
| of obesity, showing that heredity does not explain | | | | depending on the disease taken into account in |
| everything. Furthermore, it is unlikely that the human | | | | assessing the costs and the proportion of cases |
| genome has changed in the space of one generation | | | | attributable to obesity-related illnesses each. Thus, a |
| to the point of causing the obesity epidemic raging. | | | | recent U.S. study estimated $ 238 billion (253 billion |
| The fact that, globally, overweight affects more | | | | euros) the expenditure incurred in the United States |
| people than the current generation of parents and | | | | to treat diseases related to obesity such as diabetes |
| grandparents, shows that other factors are to blame. | | | | and cardiovascular disease, these data do not take |
| Indeed, the rapid changes of environment and | | | | include expenditures related to treatment of obesity |
| behavior in recent decades are major determinants | | | | itself. In Canada, the direct cost attributable to |
| of the rapid development of this disease. And it is | | | | obesity treatment has been estimated at more than |
| primarily in dietary habits and lifestyle that are the | | | | 1.8 billion Canadian dollars in 1997 (1.3 billion euros), |
| root causes of the obesity epidemic. | | | | while in France the cost was $ 11.9 million francs in |
| Eating foods with high calories and high in fat, coupled | | | | 1992 (1.8 million). |
| with a lifestyle more sedentary plays a role in the | | | | The treatment of obesity is so complicated that it is |
| development of overweight and obesity trends | | | | better not to accumulate excess weight rather than |
| around. Remember that gaining weight is never the | | | | trying to lose. It is therefore important to adopt |
| result of an imbalance of energy balance, that is to | | | | preventive measures to avoid the occurrence of |
| say between calorie intake and food use by the | | | | overweight among children and the installation of |
| organization (to operate and maintain body | | | | obesity in adults. The only way not to gain weight is |
| temperature ). When food intake exceeds energy | | | | to limit energy intake and exercise physical activity, |
| expenditure, excess energy is stored as body fat. If | | | | prevention campaigns should focus on the acquisition |
| this mechanism is set aside has enabled man to | | | | of basic knowledge about nutrition and proper eating |
| overcome periods of scarcity, it seems to serve in | | | | habits while encouraging regular exercise. This is to |
| times of glut. | | | | establish a healthy lifestyle, and not to develop |
| Far from being merely a matter of aesthetics, being | | | | obsessive behavior for weight control. It should |
| overweight causes many health complications: | | | | perhaps be guided by the preventive methods |
| respiratory disorders, hypertension, cardiovascular | | | | developed in Finland, the only country to have |
| disease, metabolic disorders (diabetes type 2, | | | | stabilized their numbers. |
| noninsulin-dependent diabetes says bold), rheumatic | | | | |