Statins and Global Transient Amnesia

Earlier this week a reader commented on a book bymemory. That is to say, whatever is happening
Dr. Duane Graveline entitled, Lipitor: Thief of Memory.around one cannot be put into any context involving
I had heard of Dr. Graveline earlier and was intendingone's past and identity. A patient is able to speak,
to comment some time in future on his work. I havebut cannot carry out a coherent conversation as
not yet read Lipitor Thief of Memory or Dr.they cannot recall more than the past few moments
Graveline's more recent work Statin Drug Sideof words. Often they are described as quite
Effects however after reading the comment Iearnestly repeating a question or statement, "as if a
realized that I can't always wait until I have becomefragment of a sound track is being repeatedly rerun".
perfectly expert in hundreds of topics beforeMotor skills are unaffected and even complex
deciding that they are worth discussion, really, therebehaviors may be carried out successfully, as one
might be one post a season if I did that. I am entirelypatient has been reported to have continued putting
confident from what I do know now that this topic istogether the alternator in his car despite the attack.
worth further discussion.The victim also retains a knowledge of self and
Dr. Graveline has an eclectic and storied background.family members yet is disoriented to space and time
He is both a former NASA astronaut as well asand cannot put the events occurring around him or
military flight surgeon and retired family practitioner.her into any coherent context. Fortunately, as the
He holds a Doctorate of Medicine as well as aname implies, the amnesia is transient generally
Masters degree in Public Health. Dr Graveline, itresolving after an average of about six hours.
appears, did not start out to become a critic of statinAll went well for Dr. Graveline until one year later,
drugs, rather the controversy found him. As hewhen he again started on Lipitor, this time at one half
describes on his website Spacedoc.net, after anhis previous dose. As Dr. Graveline describes it,
annual physical as part of his astronaut program he"Six weeks later I again descended into the black pit
was started on Lipitor for elevated cholesterol. Whileof amnesia--this time for twelve hours, and with a
there were no immediate reactions, as Dr. Gravelineretrograde loss of memory back to my high school
relates,days.
"All was well until six weeks later, when my wifeDuring that terrible interval, when my entire adult life
found me walking aimlessly about the yard after Ihad been eradicated, I had no awareness of my
returned from my usual walk in the woods. I did notmarriage or my four children; my medical school days
recognize her, and only reluctantly accepted cookiesor my ten adventure-filled years as a USAF flight
& milk--but refused to go into my now unfamiliarsurgeon; my selection as a NASA scientist-astronaut
home.or my post-retirement decade as a writer of medical
I "awoke" six hours later in the office of thefiction.
examining Neurologist with a diagnosis of transientThe names of my books were like the names of my
global amnesia, cause unknown."children - gone from my mind as completely as if
A full medical work-up found no obvious cause forthey had never happened. Fortunately (and typically
this alarming event and Dr. Graveline over thefor this obscure condition), my memory returned
protests of his doctors chose to discontinue hisspontaneously and again I drove home listening to
Lipitor treatment. Transient Global Amnesia ismy wife's amazing tale of how the day's events had
characterized by an inability to integrate short termunfolded.