Vitamin D Deficiency and Cancer

New and exciting scientific research indicates thata sophisticated analytical technique, examined the
vitamin D may help to prevent cancer as well asdata from five previous observational studies.  The
other chronic diseases.  Many of us have wronglystudy examined the effect of vitamin D on colorectal
assumed that our vitamin D levels are adequate sincecancer risk, with a follow-up of 25 years. Results
we drink milk, are exposed to the sun, and take ashowed that increased serum levels up to 34  ng/ml
multivitamin.  However, it is now known that even reduced the incidence rates of colorectal cancer by
with these activities, most people have a vitamin Dhalf.  Rates were reduced even further with higher
deficiency. This deficiency may play a role in causingserum levels.
serious illness such as heart disease, hypertension,What is vitamin D and where do we get it?
and other diseases, but in particular, cancer. TheVitamin D is not an actual vitamin, but an inactive fat
following is information from current research onsoluble pre-hormone (inactive precursor to a
vitamin D and its association with cancer.hormone).  It helps the body absorb and regulate
What is the Association between Vitamin D andcalcium and phosphorus.  There are two major
cancer?forms, D(2) (ergocalciferol) and D(3)
While vitamin D is essential for bone formation,(Cholecalciferol).  D(2) is made by plants while D(3) is
growth and repair, new research studies suggest thatmade by the body, via exposure to ultraviolent
it is also associated with a reduced risk of breast,radiation (UVB-radiation) from the sun.  The body
prostrate, and colorectal cancer.  These studies,modifies both forms in the liver to an active form
showing a possible cancer-protective role, were(Calcitriol) and then further modifies it in the kidneys
performed in laboratory experiments on cancer cellsto 1, 25-dihydrovitamin D, the form used by the
in culture, and in randomized clinical trials. Severalbody.
studies have shown the following effects on cancer.We also get vitamin D from our diet from fatty fish,
- Prostate cancer- cells contain receptors for thefish liver oil and eggs as well as from fortified foods
active form of vitamin D and respond to vitamin Dsuch as milk juice yogurt, bread and cereal. 
(3) with decreases in cell growth, invasiveness and However, both the D(2) and D(3) forms are
metastasis, and increases  in  cell death.commercially available as dietary supplements.
- Breast cancer Cedric Garland at the University of What is the Right amount of Vitamin D to take?
California in San Diego, and other prominentThis question is not an easy one to answer.  The
researchers, in a study involving more than 120,000answer depends on many personal factors.  The
women determined that women with vitamin D levelsamount needed varies with age, body weight,
above 52 ng/ml have half the risk of developingpercent body fat, season of the year, skin color,
breast cancer as those with 13 ng/ml.  Thelatitude, lactation, amount of sun exposure and the
researchers estimate that 58,000 new cases ofuse of sun-block.  It is suggested that those who
breast cancer in the United States could beare not exposed to the sun as often should take
prevented per year by raising levels to 52 ng/ml.more.
- Colorectal cancer- A new study using meta-analysis,The recommended serum levels are now 50 ng/ml.